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Revolutionizing Pancreatic Cancer Treatment: The Promise of Personalized mRNA Vaccines in a Groundbreaking Clinical Trial

Revolutionizing Pancreatic Cancer Treatment: The Promise of Personalized mRNA Vaccines in a Groundbreaking Clinical Trial

The Memorial Sloan Kettering Cancer Center is conducting a phase 2 trial of a personalized mRNA vaccine, a technology first proven effective during the COVID-19 pandemic, for pancreatic cancer patients. The vaccine targets specific proteins, neoantigens, in pancreatic tumors to stimulate an immune response. The phase 1 trial showed promising results, halting recurring cancer in roughly half the participants. The phase 2 trial aims to enroll 260 global patients and pairs the vaccine with an immunotherapy drug and chemotherapy to reduce the risk of cancer recurrence post-surgery. If successful, this approach could potentially apply to other cancers and significantly improve survival rates. However, challenges in identifying suitable neoantigens and understanding non-responsive patients remain. The trial could unravel these issues while gathering data on the vaccine's safety, efficiency, and possible side effects.

Full article here: https://lawsuithelpdesk.com/revolutionizing-pancreatic-cancer-treatment-the-promise-of-personalized-mrna-vaccines-in-a-groundbreaking-clinical-trial/

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