The 2023 AABB guidelines have significantly modernized transfusion medicine, birthing novel strategies such as high-dose cryoprecipitate and resuscitative endovascular balloon occlusion for improved hemorrhage control. Despite these innovations, there is a lack of diversity in blood donations, creating an equity issue that requires immediate redressal. Existing techniques like small-volume blood collection tubes are recommended, minimizing transfusion needs and enhancing patient outcomes. Emergent approaches like high-dose cryoprecipitate offer notable progress in trauma management. However, it's paramount to address donation disparities, particularly in marginalized communities, to foster a more inclusive system. As we reshape transfusion medicine and hemorrhage control, we must strive for universal best possible patient care, regardless of each individual's unique circumstances or location.
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