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Unraveling Cancer's Cunning: How Cancer Hijacks Immune System Pathways and the Game-Changing Potential of STING Inhibition Therapy

Unraveling Cancer’s Cunning: How Cancer Hijacks Immune System Pathways and the Game-Changing Potential of STING Inhibition Therapy

A new study from Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine has discovered cancer's exploitation of our immune system's STING pathway. Using a computational tool called ContactTracing, the study revealed that persistent activation of STING pathways aids cancer's spread by attracting immune cells that suppress natural defenses against tumors. This finding not only challenges our comprehension of the immune system's relationship with cancer, but also provides possibilities for new treatments. Inhibiting the STING pathway showed potential in reducing metastasis in preclinical tests of melanoma, breast, and colorectal cancer, suggesting STING inhibitors could prove beneficial in treating advanced cancers, especially those triggered by chromosomal instability. The discovery also points to personalized medicine's potential, enabling tailoring cancer therapies to individual's genetic and immune profiles. This pushes us closer to defeating this formidable disease.

Full article here: https://medium.com/@lawsuithelpdesk/unraveling-cancers-cunning-how-cancer-hijacks-immune-system-pathways-and-the-game-changing-aacf196e16eb

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